immunomodulatory drug


immunomodulatory drug

Clinical pharmacology A therapeutic agent that suppresses the immune system, inhibiting lymphocyte functions, especially T and NK cells; IDs are used to treat IBD–ulcerative colitis, Crohn's disease Examples Azathioprine, mercaptopurine Adverse effects BM suppression, pancreatitis; ↑ lymphoma; cyclosporine Adverse effects Renal dysfunction; MTX Adverse effects BM suppression, liver toxicity