释义 |
immunoproliferative small intestinal disease
im·mu·no·pro·lif·er·a·tive small in·tes·ti·nal dis·easediffuse lymphoplasmacytic infiltration of the proximal small bowel mucosa and mesenteric lymph nodes resulting in diarrhea, weight loss, abdominal pain, and clubbing of fingers and toes; seen in poor people in developing countries. Synonym(s): Mediterranean lymphomaimmunoproliferative small intestinal disease, IPSIDA rare mucosal lymphoma of the small intestine, associated with infection with Campylobacter jejuni. In this disease the small intestine fills with plasma cells that secrete an incomplete immunoglobulin, one in which an alpha heavy chain of the immunoglobulin molecule is formed without an associated light chain. Synonym: Mediterranean lymphoma; alpha heavy chain diseaseSee IPSID See IPSID |