granuloma pyogenicum

py·o·gen·ic gran·u·lo·ma

, granuloma pyogenicuman acquired small rounded mass of highly vascular granulation tissue, frequently with an ulcerated surface, projecting from the skin, especially of the face, or oral mucosa; histologically, the mass is a lobular capillary hemangioma. Synonym(s): lobular capillary hemangioma

py·o·gen·ic gran·u·lo·ma

, granuloma pyogenicum (pī'ō-jen'ik gran'yū-lō'mă, pī-ō-jen'i-kŭm) An acquired small, rounded mass of highly vascular granulation tissue, frequently with an ulcerated surface, projecting from the skin or mucosa; histologically, the mass resembles a capillary hemangioma.
Synonym(s): lobular capillary hemangioma.

granuloma

(gran?yu-lo'ma ) (gran?yu-lo'ma-ta) plural.granulomasplural.granulomata [ granulo- + -oma] An inflammatory response that results when macrophages are unable to destroy foreign substances that have entered or invaded body tissues. Large numbers of macrophages are drawn to the affected area over 7 to 10 days, surround the target, and enclose it. They in turn are surrounded by polymorphonuclear leukocytes, other immune cells, and fibroblasts. Granulomas are common in many conditions, including leprosy, tuberculosis, cat scratch disease, some fungal infections, and foreign body reactions, e.g., reactions to sutures. granulomatous (gran?yu-lo'ma-tus), adjective See: giant cell; tuberculosis; Wegener granulomatosis

GRANULOMA ANNULARE

granuloma annulare

A circular rash with a raised red border, usually found on the hands, knuckles, or arms of young patients. The cause is unknown. The rash often lasts 1 or 2 years and then may disappear spontaneously. See: illustration

apical granuloma

Dental granuloma.

benign granuloma of the thyroid

A lymphadenoma of the thyroid.

coccidioidal granuloma

A chronic, generalized granuloma caused by the fungus Coccidioides immitis. See: coccidioidomycosis

dental granuloma

A granuloma developing at the tip of a tooth root, usually the result of pulpitis. It consists of a proliferating mass of chronic inflammatory tissue and possibly epithelial nests or colonies of bacteria. It may be encapsulated by fibrous tissue of the periodontal ligament. Synonym: apical granuloma; apical periodontitis

eosinophilic granuloma

A form of xanthomatosis accompanied by eosinophilia and the formation of cysts on bone.

granuloma fissuratum

A circumscribed, firm, fissured, fibrotic, benign tumor caused by chronic irritation. It may occur where hard objects such as dentures or the earpieces of glasses rub against the labioalveolar fold or the retroauricular fold. The tumor disappears when the irritating object is removed.

foreign body granuloma

Chronic inflammation around foreign bodies such as sutures, talc, splinters, or gravel. Synonym: foreign body reaction

granuloma fungoides

Mycosis fungoides.

infectious granuloma

Any infectious disease in which granulomas are formed, e.g., tuberculosis or syphilis. Granulomas are also formed in mycoses and protozoan infections.

granuloma inguinale

A granulomatous ulcerative disease in which the initial lesion commonly appears in the genital area as a painless nodule.

Etiology

This type of granuloma is caused by a short, gram-negative bacillus, Calymmatobacterium granulomatis, (“Donovan body”).

Treatment

Erythromycin, trimethoprim-sulfamethoxazole, or tetracyclines are used in treating this disease. Single-dose therapy with intramuscular ceftriaxone or oral ciprofloxacin may be effective.

granuloma iridis

A granuloma that develops on the iris.

lipoid granuloma

A granuloma that contains fatty tissue or cholesterol.

lipophagic granuloma

A granuloma in which the macrophages have phagocytosed the surrounding fat cells.

Majocchi granuloma

Majocchi disease.

malignant granuloma

Hodgkin disease.

pyogenic granuloma

See: lobular capillary hemangioma