granulomatous disease


chron·ic gran·u·lom·a·tous dis·ease

a congenital defect in the killing of phagocytosed bacteria by polymorphonuclear leukocytes, which cannot increase their oxygen metabolism due to dysfunctional NADPH oxidase, either because of defective cytochrome [MIM*233710 and MIM*233690] or other specific factor deficiencies [MIM*233700 and MIM*306400]. As a result there is an increased susceptibility to severe infection by catalase-positive microorganisms; inheritance is usually autosomal recessive or X-linked. Synonym(s): congenital dysphagocytosis, granulomatous disease

granulomatous disease

(1) A nonspecific term for any disease characterised by multiple granulomas.
(2) Chronic granulomatous disease, see there.

Granulomatous disease

Characterized by growth of tiny blood vessels and connective tissue.Mentioned in: Percutaneous Transhepatic Cholangiography