hyperviscosity syndrome


hyperviscosity

 [hi″per-vis-kos´ĭ-te] excessive viscosity, as of the blood.hyperviscosity syndrome any of various syndromes associated with increased viscosity of the blood. One type is due to serum hyperviscosity and is characterized by spontaneous bleeding with neurologic and ocular disorders. Another type is characterized by polycythemia with retarded blood flow, organ congestion, reduced capillary perfusion, and increased cardiac effort. A third group includes conditions in which the deformability of erythrocytes is impaired, such as sickle cell anemia.

hy·per·vis·cos·i·ty syn·drome

a syndrome resulting from increased viscosity of the blood; an increase in serum proteins may be associated with bleeding from mucous membranes, retinopathy, and neurologic symptoms, and is sometimes seen in Waldenström macroglobulinemia and in multiple myeloma; an increased viscosity secondary to polycythemia may be associated with organ congestion and decreased capillary perfusion.

hyperviscosity syndrome

Lab medicine A clinical condition caused by an abnormal sluggishness of blood flow through peripheral vessels, especially with serum IgM levels > 3 g/dL, which may trigger oronasal bleeding, blurred vision, headache, dizziness, vertigo, ataxia, encephalopathy, or altered consciousness Funduscopic exam Venous dilatation, "sausage formation" hemorrhages, exudates; serum viscosity correlates poorly with clinical findings among Pts, but correlates well in the same Pt. See Waldenström's macroglobulinemia.

hy·per·vis·cos·i·ty syn·drome

(hīpĕr-vis-kosi-tē sindrōm) Disorder due to increased viscosity of the blood; an increase in serum proteins may be associated with bleeding from mucous membranes, retinopathy, and neurologic symptoms, and is sometimes seen in Waldenström macroglobulinemia and in multiple myeloma.