Hutchinson-Gilford disease

pro·ge·ri·a

(prō-jē'rē-ă), [MIM*176670] A condition of precocious aging with onset at birth or early childhood; characterized by growth retardation, a senile appearance with dry wrinkled skin, total alopecia, and birdlike facies; early occurrence of atherosclerosis in blood vessels and premature death due to coronary artery disease; genetics unclear. Synonym(s): Hutchinson-Gilford disease, Hutchinson-Gilford syndrome, premature senility syndrome [pro- + G. gēras, old age]

pro·ge·ri·a

(prō-jēr'ē-ă) A condition in which normal development in the first year is followed by gross retardation of growth, with a senile appearance characterized by dry, wrinkled skin, total alopecia, and birdlike facies; genetics unclear.
Synonym(s): Hutchinson-Gilford disease. [pro- + G. gēras, old age]

Hutchinson-Gilford disease

(hutch'in-son-gil'ford) [Sir Jonathan Hutchinson; Hastings Gilford, Brit. physician, 1861–1941.] Progeria.

Gilford,

Hastings, English physician, 1861-1941. Hutchinson-Gilford disease - see under Hutchinson, Sir JonathanHutchinson-Gilford syndrome - Synonym(s): Hutchinson-Gilford disease

Hutchinson,

Sir Jonathan, English surgeon and pathologist, 1828-1913. Hutchinson crescentic notch - the semilunar notch on the incisal edge of Hutchinson teeth, encountered in congenital syphilis.Hutchinson disease - age-related guttate choroiditis.Hutchinson facies - the peculiar facial expression produced by drooping eyelids and motionless eyes in external ophthalmoplegia.Hutchinson freckle - a brown or black mottled, irregularly outlined, slowly enlarging lesion. Synonym(s): lentigo malignaHutchinson mask - the sensation experienced in tabetic neurosyphilis as if the face were covered with a mask or with cobwebs.Hutchinson patch - interstitial or parenchymatous keratitis giving rise to neovascularization of the cornea. Synonym(s): salmon patchHutchinson pupil - dilation of the pupil on the side of the lesion as part of a third nerve palsy.Hutchinson teeth - the teeth of congenital syphilis in which the incisal edge is notched and narrower than the cervical area. Synonym(s): notched teeth; screwdriver teeth; syphilitic teethHutchinson triad - parenchymatous keratitis, labyrinthine disease, and Hutchinson teeth, significant of congenital syphilis.Hutchinson-Gilford disease - a condition in which normal development in the first year is followed by gross retardation of growth, with dry wrinkled skin, total alopecia, and birdlike facies. Synonym(s): Hutchinson-Gilford syndrome; progeriaHutchinson-Gilford syndrome - Synonym(s): Hutchinson-Gilford disease

单词	hutchinson-gilford disease
释义	DictionarySeeprogeria Hutchinson-Gilford disease pro·ge·ri·a (prō-jē'rē-ă), [MIM176670] A condition of precocious aging with onset at birth or early childhood; characterized by growth retardation, a senile appearance with dry wrinkled skin, total alopecia, and birdlike facies; early occurrence of atherosclerosis in blood vessels and premature death due to coronary artery disease; genetics unclear. Synonym(s): Hutchinson-Gilford disease, Hutchinson-Gilford syndrome, premature senility syndrome [pro- + G. gēras,* old age] pro·ge·ri·a (prō-jēr'ē-ă) A condition in which normal development in the first year is followed by gross retardation of growth, with a senile appearance characterized by dry, wrinkled skin, total alopecia, and birdlike facies; genetics unclear. Synonym(s): Hutchinson-Gilford disease. [pro- + G. gēras, old age] Hutchinson-Gilford disease (hutch'in-son-gil'ford) [Sir Jonathan Hutchinson; Hastings Gilford, Brit. physician, 1861–1941.] Progeria. Gilford, Hastings, English physician, 1861-1941. Hutchinson-Gilford disease - see under Hutchinson, Sir JonathanHutchinson-Gilford syndrome - Synonym(s): Hutchinson-Gilford disease Hutchinson, Sir Jonathan, English surgeon and pathologist, 1828-1913. Hutchinson crescentic notch - the semilunar notch on the incisal edge of Hutchinson teeth, encountered in congenital syphilis.Hutchinson disease - age-related guttate choroiditis.Hutchinson facies - the peculiar facial expression produced by drooping eyelids and motionless eyes in external ophthalmoplegia.Hutchinson freckle - a brown or black mottled, irregularly outlined, slowly enlarging lesion. Synonym(s): lentigo malignaHutchinson mask - the sensation experienced in tabetic neurosyphilis as if the face were covered with a mask or with cobwebs.Hutchinson patch - interstitial or parenchymatous keratitis giving rise to neovascularization of the cornea. Synonym(s): salmon patchHutchinson pupil - dilation of the pupil on the side of the lesion as part of a third nerve palsy.Hutchinson teeth - the teeth of congenital syphilis in which the incisal edge is notched and narrower than the cervical area. Synonym(s): notched teeth; screwdriver teeth; syphilitic teethHutchinson triad - parenchymatous keratitis, labyrinthine disease, and Hutchinson teeth, significant of congenital syphilis.Hutchinson-Gilford disease - a condition in which normal development in the first year is followed by gross retardation of growth, with dry wrinkled skin, total alopecia, and birdlike facies. Synonym(s): Hutchinson-Gilford syndrome; progeriaHutchinson-Gilford syndrome - Synonym(s): Hutchinson-Gilford disease
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