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hyaluronic acid
hy·a·lu·ron·ic acid H0339525 (hī′ə-lo͝o-rŏn′ĭk)n. A glycosaminoglycan that is found in extracellular tissue space, the synovial fluid of joints, and the vitreous humor of the eyes and acts as a binding, lubricating, and protective agent. [Greek hualos, glass + -uronic.]hyaluronic acid (ˌhaɪəlʊˈrɒnɪk) n (Biochemistry) a viscous polysaccharide with important lubricating properties, present, for example, in the synovial fluid in joints[C20: hyalo- + Greek ouron urine + -ic] ˌhyaluˈronic adjhy′a•lu•ron′ic ac′id (ˈhaɪ ə lʊˈrɒn ɪk, ˌhaɪ-) n. a mucopolysaccharide serving as a viscous medium in the tissues of the body and as a lubricant in joints. [1930–35; hyal (oid) (in reference to the vitreous humor, from which it was first isolated) + uronic acid] ThesaurusNoun | 1. | hyaluronic acid - a viscous mucopolysaccharide found in the connective tissue space and the synovial fluid of movable joints and the humors of the eye; a cementing and protective substancevitreous body, vitreous humor, vitreous humour - the clear colorless transparent jelly that fills the posterior chamber of the eyeballsynovia, synovial fluid - viscid lubricating fluid secreted by the membrane lining joints and tendon sheaths etc.mucopolysaccharide - complex polysaccharides containing an amino group; occur chiefly as components of connective tissue | Translationshyaluronic acid
hyaluronic acid: see mucopolysaccharidemucopolysaccharide , class of polysaccharide molecules, also known as glycosaminoglycans, composed of amino-sugars chemically linked into repeating units that give a linear unbranched polymeric compound. ..... Click the link for more information. .Hyaluronic acid A polysaccharide which is an integral part of the gel-like substance of animal connective tissue; it supposedly serves as a lubricant and shock absorbent in the joints. Hyaluronic acid has also been isolated from umbilical cord, synovial fluid, skin, certain fowl tumors, and other sources. Treatment of this polysaccharide with the enzyme hyaluronidase, followed by acid hydrolysis, yields a disaccharide consisting of N-acetyl- d -glucosamine and d -glucuronic acid. This disaccharide appears to be the basic repeating structural unit that constitutes the hyaluronic acid molecule. See Hyaluronidase, Polysaccharide Hyaluronic Acid an acidic mucopolysaccharide that consists of repeating units of α-glucuronide-N-acetylglucosamine: It is widespread in animal and human tissues. Molecular weight, 200,000-500,000 and higher. Present in skin, synovia, and the coverings of egg cells. Hyaluronic acid is an important component of the main material of connective tissue. Its solutions are very viscous; therefore, it can reduce the penetrability of tissues, preventing pathogens from penetrating into them. Hyaluronic acid is rapidly metabolized in the body, where its half-life is two days. The enzymatic hydrolysis of hyaluronic acid to acetylglucosamine and glucuronic acid is effected by hyaluronidase, which is present in the walls of pathogens, semen, the salivary secretions of leeches, rapidly growing tumors, and snake, spider, and bee venom. The hyaluronidase of microbes and venom, which destroys the hyaluronic acid of intercellular material, promotes the spread of infection deep inside body tissues. Sperm hyaluronidase, in destroying the follicular layer of the egg cell, creates favorable conditions for its fertilization. Hyaluronidase is used as a medicinal preparation to accelerate liquid absorption when the body is dehydrated, as a factor to facilitate the rapid penetration of anesthetics, and to promote the growth of connective tissue after various traumas. V. V. MAL’TSEVA hyaluronic acid[¦hī·ə·lu̇¦rän·ik ′as·əd] (biochemistry) A polysaccharide found as an integral part of the gellike substance of animal connective tissue. hyaluronic acid
hyaluronic acid [hi″ah-loo͡-ron´ik] a glycosamino-glycan found in lubricating proteoglycans of synovial fluid, vitreous humor, cartilage, blood vessels, skin, and the umbilical cord.hy·a·lu·ron·ic ac·id (hī'ă-lū-ron'ik as'id), A mucopolysaccharide consisting of alternating β1,4-linked residues of hyalobiuronic acid, forming a gelatinous material in the tissue spaces and acting as a lubricant and shock absorbant generally throughout the body; it is hydrolyzed to disaccharide or tetrasaccharide units by hyaluronidase.hyaluronic acid (hī′ə-lo͝o-rŏn′ĭk)n. A glycosaminoglycan that is found in extracellular tissue space, the synovial fluid of joints, and the vitreous humor of the eyes and acts as a binding, lubricating, and protective agent.hy·a·lu·ron·ic ac·id (hī'ă-lūr-on'ik as'id) A mucopolysaccharide forming a gelatinous material in the tissue spaces and acting as a lubricant and shock absorbant; hydrolyzed by hyaluronidase. hyaluronic acid Hyaluronate, a long polymer glycosaminoglycan, consisting of repeating disaccharide units, found in basement membranes, mature oocytes, skin, cartilage, the vitreous body of the eye and the synovial fluid of joints.hy·a·lu·ron·ic ac·id (hī'ă-lūr-on'ik as'id) A mucopolysaccharide forming a gelatinous material in the tissue spaces and acting as a lubricant and shock absorbant. See HA See HYAhyaluronic acid
Words related to hyaluronic acidnoun a viscous mucopolysaccharide found in the connective tissue space and the synovial fluid of movable joints and the humors of the eyeRelated Words- vitreous body
- vitreous humor
- vitreous humour
- synovia
- synovial fluid
- mucopolysaccharide
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