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hybridomaenUK
hy·brid·o·ma H0340200 (hī′brĭ-dō′mə)n. A cell that is produced in the laboratory by fusing an antibody-producing lymphocyte (which does not readily divide) with a nonantibody-producing cancer cell (which divides rapidly). The hybridoma proliferates and produces a continuous supply of a specific monoclonal antibody.hybridoma (ˌhaɪbrəˈdəʊmə) n (Biochemistry) a hybrid cell formed by the fusion of two different types of cell, esp one capable of producing antibodies, but of limited lifespan, fused with an immortal tumour cell[C20: from hybrid + -oma]hy•brid•o•ma (ˌhaɪ brɪˈdoʊ mə)
n., pl. -mas. a hybrid cell made in the laboratory by fusing a normal cell with a cancer cell, usu. a myeloma or lymphoma, in order to combine desired features of each, as the ability of the cancer cell to multiply rapidly with the ability of the normal cell to dictate the production of a specific antibody. [1975–80] Thesaurus| Noun | 1. | hybridoma - a hybrid cell resulting from the fusion of a lymphocyte and a tumor cell; used to culture a specific monoclonal antibodysomatic cell, vegetative cell - any of the cells of a plant or animal except the reproductive cells; a cell that does not participate in the production of gametes; "somatic cells are produced from preexisting cells"; |
TranslationshybridomaenUK
hybridoma[‚hī·brə′dō·mə] (immunology) A hybrid myeloma formed by fusing myeloma cells with lymphocytes that produce a specific antibody; the individual cells can be cloned, and each clone produces large amounts of identical (monoclonal) antibody. hybridomaenUK
hybridoma [hi″brĭ-do´mah] a somatic cell hybrid formed by fusion of normal lymphocytes and tumor (lymphoma) cells. B cell hybridomas are the most useful source of monoclonal antibodies; the hybridoma cells are able to produce antibody like the normal parent and to proliferate indefinitely in culture like the parent tumor cells.hy·brid·o·ma (hī'brid-ō'mă), A tumor of hybrid cells used in the in vitro production of specific monoclonal antibodies; produced by fusion of an established tissue culture line of lymphocyte tumor cells (for example, mouse plasmacytoma cells) and specific antibody-producing cells (for example, splenocytes from specifically immunized mice). Fusions are accomplished by use of polyethylene glycol or other methods. [G. hybris, violation, wantonness, + -ōma, tumor] hybridoma (hī′brĭ-dō′mə)n. A cell that is produced in the laboratory by fusing an antibody-producing lymphocyte (which does not readily divide) with a nonantibody-producing cancer cell (which divides rapidly). The hybridoma proliferates and produces a continuous supply of a specific monoclonal antibody.hy·brid·o·ma (hī'brid-ō'mă) A tumor of hybrid cells used in the production in vitro of specific monoclonal antibodies; produced by fusion of an established tissue culture line of lymphocyte tumor cells and specific antibody-producing cells. [G. hybris, violation, wantonness, + -ōma, tumor]hybridoma A cell line (CLONE) formed by the fusion of two or more different types of cells, such as a B LYMPHOCYTE and a lymphoid tumour cell (myeloma). Malignant tumours can be immortal so a hybridoma, suitably nourished, can continue permanently exercising the function of the B lymphocyte to produce specific antibodies (MONOCLONAL ANTIBODIES).hybridoma a cell made by fusing an antibody-producing B-CELL with a CANCER cell. The cancer cell contributes the ability to divide indefinitely, while the antibody cell contributes the ability to synthesize large amounts of a single antibody A hybridoma CLONE forms as a result of division of this hybrid, and can be maintained indefinitely in culture, producing large amounts of pure antibody The antibodies produced by a specific hybridoma clone are identical, they are MONOCLONAL ANTIBODIES.hybridomaenUK
Words related to hybridomanoun a hybrid cell resulting from the fusion of a lymphocyte and a tumor cellRelated Words- somatic cell
- vegetative cell
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