hypotrichosis type 6
hypotrichosis type 6
An autosomal recessive condition (OMIM:607903) characterised by a relative paucity of hair, involving mainly the scalp, chest, arms and legs, with abnormal thin and atrophic hair follicles and hair shafts.Molecular pathology
Defects in DSG4, which encodes desmoglein 4, a component of intercellular desmosomes that mediate cell–cell adhesion, cause hypotrichosis type 6.