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homogentisic acid
Thesaurus| Noun | 1. | homogentisic acid - an acid formed as an intermediate product of the metabolism of tyrosine and phenylalaninealcapton, alkaptonacid - any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt |
Homogentisic Acid
homogentisic acid[¦hä·mə‚jen¦tiz·ik ′as·əd] (biochemistry) C8H8O4 An intermediate product in the metabolism of phenylalanine and tyrosine; found in excess in persons with phenylketonuria and alkaptonuria. Homogentisic Acid an intermediate product of the decomposition of the cyclic amino acids phenylalanine and tyrosine in the animal or human body. In the hereditary disease alkaptonuria, which is expressed in a disturbance of the metabolism of these amino acids, the process stops at the stage of homogentisic acid formation because of an absence of homogentisic acid oxidase, and homogentisic acid is discharged with the urine. homogentisic acid
homogentisic acid [ho″mo-jen-tis´ik] 2,5-dihydroxyphenyl acetic acid, an intermediate product in the metabolism of tyrosine and phenylalanine, excreted in the urine in the error of metabolism" >inborn error of metabolism known as phenylketonuria.ho·mo·gen·tis·ic ac·id (hō'mō-jen-tis'ik as'id), Glycosuric acid; (2,5-dihydroxyphenyl)acetic acid; an intermediate in l-phenylalanine and l-tyrosine catabolism; if made alkaline, it oxidizes rapidly in air to a quinone that polymerizes to a melaninlike material; elevated levels are observed in patients with alcaptonuria. Synonym(s): alcapton, alkaptonhomogentisic acid (hō′mō-jĕn-tĭz′ĭk)n. An intermediate of the metabolic breakdown of tyrosine and phenylalanine; it occurs in the urine in cases of alkaptonuria.ho·mo·gen·tis·ic ac·id (hō'mō-jen-tis'ik as'id) An intermediate in l-phenylalanine and l-tyrosine catabolism; if made alkaline, it oxidizes rapidly in air to a quinone that polymerizes to a melaninlike material; elevated levels are observed in individuals having alcaptonuria.
Synonym(s): alcapton, alkapton. homogentisic acid see GARROD, A.AcronymsSeehigh-gain antennahomogentisic acid
Related to homogentisic acid: ochronosis, alkaptonuria, alkapton, Homogentisic acid oxidaseSynonyms for homogentisic acidnoun an acid formed as an intermediate product of the metabolism of tyrosine and phenylalanineSynonymsRelated Words |