17-hydroxylase deficiency syndrome

17-hy·drox·y·lase de·fi·cien·cy syn·drome

[MIM*202110] congenital deficiency of adrenocortical and gonadal (that is, testicular and ovarian) steroid C-17α-hydroxylase; the resulting excessive secretion of corticosterone and deoxycorticosterone produces hypertension, and hypokalemic alkalosis while the low lex steroid secretion is associated with ambiguous genitalia in genetics(?) males and sexual infantilism in females. Both sexes fail to enter puberty. One of two rare causes of primary amenorrhea; autosomal recessive inheritance caused by mutation in one of the cytochrome P450 genes (CYP17) on chromosome 10q.

单词	17-hydroxylase deficiency syndrome
释义	17-hydroxylase deficiency syndrome 17-hy·drox·y·lase de·fi·cien·cy syn·drome [MIM202110] congenital deficiency of adrenocortical and gonadal (that is, testicular and ovarian) steroid C-17α-hydroxylase; the resulting excessive secretion of corticosterone and deoxycorticosterone produces hypertension, and hypokalemic alkalosis while the low lex steroid secretion is associated with ambiguous genitalia in genetics(?) males and sexual infantilism in females. Both sexes fail to enter puberty. One of two rare causes of primary amenorrhea; autosomal recessive inheritance caused by mutation in one of the cytochrome P450 genes (CYP17*) on chromosome 10q.
随便看	unskilled unskilled labor unskilled person unskilled work unskilled worker unskilled workers unskillful unskillfully unskillfulness unskimmed unskinned vinogradov, pavel gavrilovich vinogradov, pavlin vinogradov, pavlin fedorovich vinogradov, sergei vinogradov, sergei arsenevich vinogradov, vasilii vinogradov, vasilii ivanovich vinogradov, viktor vinogradov, viktor vladimirovich vinogradov, vladimir vinogradov, vladimir alekseevich vinogradskaia, katerina vinogradskaia, katerina nikolaevna vinogradskii, sergei