Honeycomb Atrophy

A rare autosomal recessive [MIM 209700] symmetric dermatopathy (genodermatosis) characterised by skin atrophy with sharply demarcated ‘pits’, variably accompanied by cardiac defects, mental retardation, neurofibromas.
Prognosis Usually slowly progressive; spontaneous regression has been reported.
Management Dermabrasion, cryotherapy, ultraviolet light radiation, topical medications, CO2 and 585 nm pulsed dye lasers