IGF-II

IGF2

A gene on chromosome 11p15.5 that encodes a protein, similar to insulin in structure and function, which belongs to a family of proteins involved in mediating growth and development. It is an imprinted gene and expressed only from the paternal allele.
Molecular pathology
Epigenetic changes at 11p15.5 are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma and Silver-Russell syndrome.

IGF-II

Insulin-like growth factor II A protein homologue of IGF-I that may be produced by tumors and cause reactive hypoglycemia ↑ in Acromegaly, hepatoma, leiomyosarcoma, mesothelioma, Wilms' tumor ↓ in hGH deficiency, infants; IGF-II receptor is similar, if not identical to the mannose-6-phosphate receptor

Acronym

Definition

IGF-II➣Insulin-Like Growth Factor II (also seen as IGF2)