释义 |
hydroxocobalamin
hydroxocobalamin [hi-drok″so-ko-bal´ah-min] an analogue of cyanocobalamin (vitamin B12) having exceptionally long-acting hematopoietic activity; used in the treatment of pernicious anemia and other macrocytic anemias.hy·drox·o·co·bal·a·min (hī-drok'sō-kō-bal'ă-min), Vitamin B12b, differing from cyanocobalamin (vitamin B12) in the presence of a hydroxyl ion in place of the cyanide ion at the sixth coordinate position on the cobalt atom. See also: vitamin B12. Synonym(s): hydroxocobeminehy·drox·y·co·bal·a·min (hī-drok'sē-kō-bal'ă-min) A chemical compound, also called vitamin B12a, which is the immediate precursor to cyanocobalamin (vitamin B12) in the body and that has also been investigated as an antidote in cyanide poisoning, although it is not currently approved for such use in the U.S. See also: amyl nitrite, sodium nitrite, sodium thiosulfate Synonym(s): hydroxocobalamin. hydroxocobalamin Vitamin B12. This is the specific treatment for PERNICIOUS ANAEMIA and is highly effective unless neurological damage has already occurred. The drug is on the WHO official list. Brand names are Cobalin-H and Neo-Cytamen. |