| Acronym | Definition |
|---|
| HPDF➣High-Performance Debugging Forum (UK) |
| HPDF➣High Power Density Focusing Optics (Castelo Enterprises, Inc.) |
| HPDF➣Highest Practical Dose and Frequency (medication research) |
| HPDF➣Habaraduwa Participatory Development Foundation (Sri Lanka) |
| HPDF➣High-Performance Data Fabric (computing) |