25-hydroxycholecalciferol 1alpha-hydroxylase

cal·ci·di·ol 1α-·hy·dro·xyl·ase, 25-hy·drox·y·cho·le·cal·cif·er·ol 1α-·hy·drox·y·lase

the monooxygenase that forms calcitriol from calcidiol using O2 and NADPH; a deficiency in this enzyme can result in features of a vitamin D deficiency.