interleukin-11

in·ter·leu·kin-11

(in'tĕr-lū'kin), A cytokine and growth factor derived from bone marrow stromal cells (endothelial cells, macrophages, and preadipocytes) that stimulates increased plasma concentrations of acute-phase proteins and is a growth factor with multiple hematopoietic effects.

IL11

A gene on chromosome 19q13.3-q13.4 that encodes interleukin-11, a member of the gp130 family of cytokines, which drive the assembly of multi-subunit receptor complexes, all of which contain at least one molecule of the transmembrane signalling receptor IL6ST. IL11 directly stimulates the proliferation of haematopoietic stem cells and megakaryocyte progenitor cells, and it induces megakaryocyte maturation resulting in increased platelet production.

in·ter·leu·kin-11

(in'tĕr-lū'kin) A cytokine derived from bone marrow stromal cells (endothelial cells, macrophages, and preadipocytes) that stimulates increased plasma concentrations of acute phase proteins.

interleukin-11

A CYTOKINE produced by bone marrow stromal cells that promotes the induction of ACUTE PHASE PROTEINS.

单词	interleukin-11
释义	DictionarySeeinterleukin interleukin-11 interleukin-11 [‚in·tər¦lük·ən i′lev·ən] (immunology) A pleiotropic cytokine produced by bone marrow-derived fibroblasts which supports the growth of certain cell types, such as B cells, neutrophils, and platelet-producing megakaryocytes. Abbreviated IL-11. interleukin-11 in·ter·leu·kin-11 (in'tĕr-lū'kin), A cytokine and growth factor derived from bone marrow stromal cells (endothelial cells, macrophages, and preadipocytes) that stimulates increased plasma concentrations of acute-phase proteins and is a growth factor with multiple hematopoietic effects. IL11 A gene on chromosome 19q13.3-q13.4 that encodes interleukin-11, a member of the gp130 family of cytokines, which drive the assembly of multi-subunit receptor complexes, all of which contain at least one molecule of the transmembrane signalling receptor IL6ST. IL11 directly stimulates the proliferation of haematopoietic stem cells and megakaryocyte progenitor cells, and it induces megakaryocyte maturation resulting in increased platelet production. in·ter·leu·kin-11 (in'tĕr-lū'kin) A cytokine derived from bone marrow stromal cells (endothelial cells, macrophages, and preadipocytes) that stimulates increased plasma concentrations of acute phase proteins. interleukin-11 A CYTOKINE produced by bone marrow stromal cells that promotes the induction of ACUTE PHASE PROTEINS.
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