interleukin-4

[‚in·tər′lük·ən ′fȯr] (immunology) A cytokine that is capable of a variety of activities, such as induction of proliferation by T cells, mast cells, megakarocytes, and erythroid precursors; induction of antibody secretion by B cells; and potentiation of the proliferation of mast cells. Abbreviated IL-4.

interleukin-4

in·ter·leu·kin-4

(in'tĕr-lū'kin), A cytokine derived from T4 lymphocytes that causes differentiation of B lymphocytes. Promotes Ig class switch and production of IgE. It stimulates DNA biosynthesis. Synonym(s): B-cell differentiating factor

IL4

A gene on chromosome 5q31.1 that encodes interleukin-4, a pleiotropic cytokine produced by activated T cells, which participates in several B-cell activation processes. IL-4 is a ligand for IL4 receptor (as is IL13), and it induces the expression of class II MHC molecules on resting B-cells. It activates several B-cell and other cell processes; is a co-stimulator of DNA-synthesis; enhances secretion and cell surface expression of IgE and IgG1; and regulates expression of the low-affinity Fc receptor for IgE (CD23) on lymphocytes and monocytes.

in·ter·leu·kin-4

(in'tĕr-lū'kin) A cytokine derived from T4 lymphocytes that causes differentiation of B lymphocytes.
Synonym(s): B-cell differentiating factor.

interleukin-4

A CYTOKINE produced by HELPER T CELLS, MAST CELLS and bone marrow that has a wide range of actions. It promotes the proliferation of B cells, T cells, MAST CELLS and blood forming cells; it induces the formation of MAJOR HISTOCOMPATIBILITY COMPLEXES on B cells; and it is believed to promote class switching in B cells from one class of antibodies to another.

单词	interleukin-4
释义	DictionarySeeinterleukin interleukin-4 interleukin-4 [‚in·tər′lük·ən ′fȯr] (immunology) A cytokine that is capable of a variety of activities, such as induction of proliferation by T cells, mast cells, megakarocytes, and erythroid precursors; induction of antibody secretion by B cells; and potentiation of the proliferation of mast cells. Abbreviated IL-4. interleukin-4 in·ter·leu·kin-4 (in'tĕr-lū'kin), A cytokine derived from T4 lymphocytes that causes differentiation of B lymphocytes. Promotes Ig class switch and production of IgE. It stimulates DNA biosynthesis. Synonym(s): B-cell differentiating factor IL4 A gene on chromosome 5q31.1 that encodes interleukin-4, a pleiotropic cytokine produced by activated T cells, which participates in several B-cell activation processes. IL-4 is a ligand for IL4 receptor (as is IL13), and it induces the expression of class II MHC molecules on resting B-cells. It activates several B-cell and other cell processes; is a co-stimulator of DNA-synthesis; enhances secretion and cell surface expression of IgE and IgG1; and regulates expression of the low-affinity Fc receptor for IgE (CD23) on lymphocytes and monocytes. in·ter·leu·kin-4 (in'tĕr-lū'kin) A cytokine derived from T4 lymphocytes that causes differentiation of B lymphocytes. Synonym(s): B-cell differentiating factor. interleukin-4 A CYTOKINE produced by HELPER T CELLS, MAST CELLS and bone marrow that has a wide range of actions. It promotes the proliferation of B cells, T cells, MAST CELLS and blood forming cells; it induces the formation of MAJOR HISTOCOMPATIBILITY COMPLEXES on B cells; and it is believed to promote class switching in B cells from one class of antibodies to another.
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