单词 | interleukin-7 |
释义 | interleukin-7interleukin-7[‚in·tər¦lük·ən ′sev·ən]interleukin-7in·ter·leu·kin-7(in'tĕr-lū'kin),IL7A gene on chromosome 8q12-q13 that encodes interleukin-7, a hematopoietic growth factor which stimulates the proliferation of lymphoid progenitors, including both B and T cells. It forms a heterodimer with hepatocyte growth factor to act as a pre-pro-B-cell growth-stimulating factor. It is also a cofactor for V(D)J rearrangement of the T-cell receptor beta during early T-cell development. IL7 is produced locally by intestinal mucosal cells, and may act as a regulatory factor for intestinal mucosal (GALT) lymphocytes.in·ter·leu·kin-7(in'tĕr-lū'kin)interleukin-7A CYTOKINE produced by the bone marrow stromal cells responsible for the proliferation of B cell precursors, helper and cytotoxic T cells and activated mature T cells. |
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