insulin-dependent diabetes mellitus type 19

A multifactorial disorder of glucose homeostasis (OMIM:610155) characterised by susceptibility to ketoacidosis in the absence of insulin therapy.
Clinical findings
Polydipsia, polyphagia, polyuria due to hyperglycaemia-induced osmotic diuresis and secondary thirst. Long-term diabetic complications affect the eyes, kidneys, nerves and blood vessels.
Molecular pathology
Defects of IFIH1, which encodes an RNA helicase, cause IDDM19.

单词	insulin-dependent diabetes mellitus type 19
释义	insulin-dependent diabetes mellitus type 19 insulin-dependent diabetes mellitus type 19 A multifactorial disorder of glucose homeostasis (OMIM:610155) characterised by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical findings Polydipsia, polyphagia, polyuria due to hyperglycaemia-induced osmotic diuresis and secondary thirst. Long-term diabetic complications affect the eyes, kidneys, nerves and blood vessels. Molecular pathology Defects of IFIH1, which encodes an RNA helicase, cause IDDM19.
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