Keshan disease


A fatal heart disease first reported in Keshan County of the greater metropolitan Qiqihar of the Heilongjiang province, mainland China, which affects children and young women; the condition has since been found elsewhere—e.g., New Zealand and Finland—where soil selenium levels are low
Pathogenesis Selenium deficiency in water supply, resulting in dilated cardiomyopathy and increased platelet aggregation due to decreased free radical salvage by glutathione peroxidase
Management Selenium

Ke·shan dis·ease

(kē'shăn di-zēz') Cardiomyopathy due to the deficiency of selenium found in women and children in Keshan, China.