BIONJ

Bisphosphonate-induced osteonecrosis of the jaw. A condition linked to the use of IV and oral nitrogen-containing bisphosphonate drugs, resulting in osteonecrosis of the jaw.
Drugs implicated
Zoledronate, pamidronate or combination thereof, used to treat breast cancer or myeloma. About 5% of those with BIONJ were being treated for osteoporosis.
Risk factors
Tooth extractions (50% of cases), mandibular exostoses, periodontal disease, trauma from ill-fitting dentures, smoking, obesity, use of cytotoxic drugs and glucocorticoids.

单词	bionj
释义	BIONJ BIONJ Bisphosphonate-induced osteonecrosis of the jaw. A condition linked to the use of IV and oral nitrogen-containing bisphosphonate drugs, resulting in osteonecrosis of the jaw. Drugs implicated Zoledronate, pamidronate or combination thereof, used to treat breast cancer or myeloma. About 5% of those with BIONJ were being treated for osteoporosis. Risk factors Tooth extractions (50% of cases), mandibular exostoses, periodontal disease, trauma from ill-fitting dentures, smoking, obesity, use of cytotoxic drugs and glucocorticoids.
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