angioimmunoblastic lymphadenopathy


lymphadenopathy

 [lim-fad″ĕ-nop´ah-the] disease of the lymph nodes" >lymph nodes; called also adenopathy.angioimmunoblastic lymphadenopathy (angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)) a systemic disorder resembling lymphoma characterized by fever, night sweats, weight loss, generalized lymphadenopathy, hepatosplenomegaly, macropapular rash, polyclonal hypergammaglobulinemia, and Coombs'-positive hemolytic anemia. It is considered to be a nonmalignant hyperimmune reaction to chronic antigenic stimulation; there is proliferation of B cells accompanied by profound deficiency of T cells. The disease follows a progressive but extremely variable course: some patients survive for a long period without chemotherapy; in other patients, overwhelming infections rapidly lead to deathdermatopathic lymphadenopathy regional lymph node enlargement associated with melanoderma and other dermatoses marked by chronic erythroderma.immunoblastic lymphadenopathy angioimmunoblastic lymphadenopathy.lymphadenopathy syndrome a condition occurring in immunocompromised individuals, characterized by unexplained lymphadenopathy for 3 or more months that involves extrainguinal sites, which on biopsy reveal nonspecific lymphoid hyperplasia. See also complex" >AIDS-related complex.

angioimmunoblastic lymphadenopathy

(1) A condition now subsumed under T-cell lymphoma.
(2) Angioimmunoblastic lymphadenopathy with dysproteinaemia.