Karrer, Paul

Karrer, Paul,

1889–1971, Swiss organic chemist, Ph.D. Univ. of Zürich, 1911. From 1912 to 1918, Karrer was a chemist at the Georg Speyer Haus, Frankfurt-am-Main. He left in 1919 to become professor of chemistry and director of the Chemical Institute at the Univ. of Zürich, where he remained until his retirement in 1953. Karrer won the 1937 Nobel Prize in Chemistry with Norman HaworthHaworth, Sir Walter Norman,
1883–1950, British chemist, Ph.D. Univ. of Göttingen, 1911. Haworth held academic posts at Imperial College of Science and Technology in London (1911–12), the Univ. of St. Andrews (1912–20), and the Univ.
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 for his investigations on carotenoids, flavins, and vitamins A and B2. Karrer is credited with being the first to isolate vitamins A and K and to synthesize vitamins B2 and E. His most significant accomplishment was elucidating the structure of carotenecarotene
, long-chained, unsaturated hydrocarbon found as a pigment in many higher plants, particularly carrots, sweet potatoes, and leafy vegetables. Carotene is thought to assist in trapping light energy for photosynthesis or to aid in chemical reduction.
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, the yellow pigment found in carrots and other orange and yellow vegetables.

Karrer, Paul

 

Born Apr. 21, 1889, in Moscow. Swiss organic chemist and biochemist. Graduated from the University of Zürich in 1911. From 1912 to 1918 he conducted pharmaco-chemical research in Frankfurt am Main with P. Ehrlich on complex metal salts and produced the silver-arsphenamine complex. He has been a professor at the University of Zürich since 1918 and director of the Institute of Chemistry in Zürich since 1919.

Karrer established the structure and conducted the synthesis of a number of biologically active natural compounds (carbohydrates, alkaloids, lecithins, anthocyanides, many carotenoids, and vitamins A, B2, E, K, and B1 and their coenzymatic forms). He and the English scientist W. Haworth shared a Nobel Prize in 1937.

WORKS

Einführung in die Chemie der polymeren Kohlenhydrate. Leipzig, 1925.
Lehrbuch der organischen Chemie, 13th ed. Stuttgart, 1959.
Carotinoide. Basel, 1948. (With E. Jucker.)
In Russian translation:
Kurs organicheskoi khimii. Leningrad, 1960.