释义 |
IRF3
IRF3 A gene on chromosome 19q13.3-q13.4 that encodes a member of the interferon regulatory transcription factor (IRF) family. IRF3 is inactive in the cytoplasm, but after serine/threonine phosphorylation forms a complex with CREBBP; the IRF3/CREBBP complex translocates to the nucleus and activates transcription of interferons alpha and beta, as well as interferon-induced genes.IRF3
Acronym | Definition |
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IRF3➣Interferon Regulatory Factor 3 | IRF3➣IFN Regulatory Factor 3 |
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