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单词 iron-deficiency anemia
释义

iron-deficiency anemia


Translations

iron-deficiency anemia


iron-deficiency anemia

[′ī·ərn də‚fish·ən·sē ə′nē·mē·ə] (medicine) Hypochromic microcytic anemia due to excessive loss, deficient intake, or poor absorption of iron. Also known as nutritional hypochromic anemia.

iron-deficiency anemia


iron-deficiency anemia

An anemia due to ↓ Hb production due to ↓ iron; in idiopathic IDA, 62% of Pts have lesions of the upper, lower, or both ends of the GI tract causing iron deficiency–ie, blood loss Clinical FTT, ↑ infections Lab Hypochromia, microcytosis. See Anemia, iron.

iron-deficiency anemia

Abbreviation: IDA
Anemia resulting from a greater demand on stored iron supplies than can be provided. The erythrocyte count may sometimes be normal, but there is insufficient hemoglobin. Erythrocytes are hypochromic and show poikilocytosis. IDA is present in about 8% of men and 14% of women ages 3 to 74 years in the U.S.

Etiology

IDA is caused by inadequate iron intake, malabsorption of iron, blood loss, pregnancy and lactation, intravascular hemolysis, or a combination of these factors.

Symptoms

Chronically anemic patients often complain of fatigue and dyspnea on exertion. Iron deficiency resulting from rapid bleeding, may produce palpitations, orthostatic dizziness, or syncope.

Diagnosis

Laboratory studies reveal decreased iron levels in the blood, with elevated iron-binding capacity and a diminished transferrin saturation. Ferritin levels are low. The bone marrow does not show stainable iron.

Additional Diagnostic Studies

Adult nonmenstruating patients with IDA should be evaluated to rule out a source of bleeding in the gastrointestinal tract.

Treatment

Dietary iron intake is supplemented with oral ferrous sulfate or ferrous gluconate (with vitamin C to increase iron absorption). Oral liquid iron supplements should be given through a straw to prevent staining of the teeth. Iron preparations cause constipation; laxatives or stool softeners should be considered as concomitant treatment. When underlying lesions are found in the gastrointestinal tract, e.g., ulcers, esophagitis, cancer of the colon, they are treated with medications, endoscopy, or surgery.

CAUTION!

Parents should be warned to keep iron preparations away from children because three or four tablets may cause serious poisoning.
See also: anemia
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