ITGA9

ITGA9

A gene on chromosome 3p21.3 that encodes an integrin alpha chain protein which, like all integrins, forms a heterodimer with a beta chain, thereby participating in cell adhesion and cell surface-mediated signalling. Alpha 9 binds to a beta-1 chain, forming a receptor for VCAM1, cytotactin and osteopontin.
Molecular pathology
ITGA9 expression is upregulated in small-cell carcinoma of the lung.