intrinsic pathway

Hematology An arm of the coagulation cascade, initiated by negatively charged surfaces–contact factors–eg, sulfatide micelles, kaolin which bind factor XII and HMW kininogen–HMWK; HMWK binds prekallikrein and factor XI, activating the latter; XIa then activates IX which in turn activates factor X, initiating the common pathway. See Common pathway, Extrinsic pathway.

Intrinsic pathway

One of three pathways in the coagulation cascade.Mentioned in: Partial Thromboplastin Time

单词	intrinsic pathway
释义	DictionarySeecoagulation intrinsic pathway intrinsic pathway Hematology An arm of the coagulation cascade, initiated by negatively charged surfaces–contact factors–eg, sulfatide micelles, kaolin which bind factor XII and HMW kininogen–HMWK; HMWK binds prekallikrein and factor XI, activating the latter; XIa then activates IX which in turn activates factor X, initiating the common pathway. See Common pathway, Extrinsic pathway. Intrinsic pathway One of three pathways in the coagulation cascade.Mentioned in: Partial Thromboplastin Time
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