angioneurotic oedema


angioneurotic oedema

(1) Acquired angioedema, a chronic and potentially fatal condition characterised by abdominal pain and episodic localised subcutaneous, periorbital, periocular and laryngeal oedema, due to an absence of C1 esterase inhibitor.
 
Clinical findings
Recurrent oedema; abdominal pain; laryngeal oedema, which may compromise breathing.
Diagnosis
History of recurrent angioedema, abnormally low or absent C1 esterase inhibitor in blood.
 
Triggers
Allergies (e.g., foods, pollen, insect bites); drugs (e.g., ACE inhibitors, salicylates); stress; exposure to cold, water, sunlight or heat.
Management
Epinephrine, antihistamines, corticosteroids (androgens).
(2) Hereditary angioneurotic oedema, see there

angioneurotic oedema

A form of allergy in which contact with certain foodstuffs, plants, drugs or pollens or an insect sting causes swelling of the lining of the nose, mouth, throat or digestive tract. The main danger is from ASPHYXIA from oedema of the LARYNX.