angioneurotic oedema
angioneurotic oedema
(1) Acquired angioedema, a chronic and potentially fatal condition characterised by abdominal pain and episodic localised subcutaneous, periorbital, periocular and laryngeal oedema, due to an absence of C1 esterase inhibitor.Clinical findings
Recurrent oedema; abdominal pain; laryngeal oedema, which may compromise breathing.
Diagnosis
History of recurrent angioedema, abnormally low or absent C1 esterase inhibitor in blood.
Triggers
Allergies (e.g., foods, pollen, insect bites); drugs (e.g., ACE inhibitors, salicylates); stress; exposure to cold, water, sunlight or heat.
Management
Epinephrine, antihistamines, corticosteroids (androgens).
(2) Hereditary angioneurotic oedema, see there