4-dinitrophenol


Sports medicine—Body-building A potent non-selective inhibitor of oxidative phosphorylation, which results in increased metabolism and increased body temperature, and has been used illegally for weight control
Toxicology Any of a family of compounds used in weed control and, at one time, for weight control, which may cause death due to the uncoupling of mitochondrial oxidative phosphorylation, resulting in increased body temperature, rapid breathing, tachycardia, nausea, flushed skin, cyanosis, collapse, coma; dinitrophenol poisoning causes rapid death or recovery in 24 hours
Management Ice baths, O2, correct fluid and electrolyte imbalances