iodoglobulin


thy·ro·glob·u·lin

(thī'rō-glob'yū-lin), [MIM*188450] 1. A protein that contains precursors of thyroid hormone usually stored in the colloid within the thyroid follicles; biosynthesis of thyroid hormone entails iodination of the l-tyrosyl moieties of this protein and the combination of two iodotyrosines to form thyroxine, the fully iodinated thyronine; secretion of thyroid hormone requires proteolytic degradation of thyroglobulin, with the attendant release of free hormone; a defect in thyroglobulin metabolism will lead to hypothyroidism. Synonym(s): iodoglobulin, thyroprotein (1) 2. A substance obtained by the fractionation of thyroid glands from the hog, Sus scrofa, containing not less than 0.7% of total iodine; used as a thyroid hormone in the treatment of hypothyroidism.

iodoglobulin

(ī″ō-dō-glŏb′ū-lĭn) [″ + L. globus, globe] A globulin that contains iodine.