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单词 islets of langerhans
释义

islets of Langerhans


is·lets of Lang·er·hans

I0249100 (ī′lĭts; läng′ər-häns′)pl.n. Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.
[After Paul Langerhans (1847-1888), German pathologist.]

islets of Langerhans

(ˈlæŋəˌhæns) or

islands of Langerhans

pl n (Anatomy) small groups of endocrine cells in the pancreas that secrete the hormones insulin and glucagon[C19: named after Paul Langerhans (1847–88), German physician]

is·lets of Lang·er·hans

(ī′lĭts əv läng′ər-häns′) Irregular clusters of endocrine cells that are scattered throughout the tissue of the pancreas and secrete insulin.
Thesaurus
Noun1.islets of Langerhans - cell clusters in the pancreas that form the endocrine part of that organ; secrete insulin and other hormonesislands of Langerhans, isles of Langerhansductless gland, endocrine gland, endocrine - any of the glands of the endocrine system that secrete hormones directly into the bloodstreampancreas - a large elongated exocrine gland located behind the stomach; secretes pancreatic juice and insulin

islets of Langerhans


islets of Langerhans:

see pancreaspancreas
, glandular organ that secretes digestive enzymes and hormones. In humans, the pancreas is a yellowish organ about 7 in. (17.8 cm) long and 1.5 in. (3.8 cm) wide. It lies beneath the stomach and is connected to the small intestine at the duodenum (see digestive system).
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Islets of Langerhans

 

the groups of cells in the pancreas of man and vertebrates (except cyclostomes) that form the endocrine part of the organ, secreting the hormones insulin and glucagon into the blood.

The islets of Langerhans are named for the German scientist P. Langerhans, who described them in 1869. In 1901, the Russian scientist L. V. Sobolev proved their endocrine function and established the occurrence of changes in the islets with diabetes mellitus. The dimensions of the islets of Langerhans are 50 to 500 microns, and there are between ten and 20 islets per mg of gland tissue. The islets do not communicate with the gland’s effluent ducts.

The islets of Langerhans develop from tubular processes of the anterior gut and, depending on the type of animal, consist of cells of several types. All animals have α cells and β cells. The granules of α cells are considered to be a form of glucagon deposit; the β cells, of insulin. C cells and D cells (the former have been found in the islets of Langerhans of guinea pigs; the latter, in man and dogs), which lack granules, are converted to α cells and β cells. In all, the tissue of the islets of Langerhans makes up 0.9 to 3.6 percent of the mass of the pancreas in children and 0.9 to 2.7 percent in adults.

V. M. SAMSONOVA

islets of Langerhans


is·lets of Lan·ger·hans

(lahng'ĕr-hahnz), cellular masses consisting of several to several hundred cells lying in the interstitial tissue of the pancreas; they are composed of five different cell types that make up the endocrine portion of the pancreas and are the sources of insulin, glucagon, somatostatin, pancreatic polypeptide, and gastrin. Synonym(s): islet tissue, Langerhans islands, pancreatic islands, pancreatic islets

islets of Langerhans

(ī′lĭts; läng′ər-häns′)pl.n. Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz) Cellular masses varying from a few to hundreds of cells lying in the interstitial tissue of the pancreas; they are the source of insulin and glucagon.

Islets of Langerhans

INSULIN secreting collections of cells lying in the INTERSTITIAL tissue of the PANCREAS. (Paul Langerhans, 1847–1888, German medical student, later anatomy professor).

islets of Langerhans

groups of cells found scattered in the pancreas of jawed vertebrates.

Islets of Langerhans

Special structures in the pancreas responsible for insulin secretion among other functions. They are named for Paul Langerhans, the German researcher who first identified them in 1869.Mentioned in: Insulin Resistance, Pancreatic Cancer, Endocrine

Langerhans,

Paul, German anatomist, 1847-1888. islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic isletsLangerhans cell granulomatosisLangerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granuleLangerhans islands - Synonym(s): islets of Langerhans

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz) Cellular masses consisting of several to several hundred cells lying in interstitial pancreatic tissue.

islets of Langerhans


Related to islets of Langerhans: insulin, pancreas, somatostatin
  • noun

Synonyms for islets of Langerhans

noun cell clusters in the pancreas that form the endocrine part of that organ

Synonyms

  • islands of Langerhans
  • isles of Langerhans

Related Words

  • ductless gland
  • endocrine gland
  • endocrine
  • pancreas
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