juvenile periodontitis


ju·ve·nile per·i·o·don·ti·tis

[MIM*170650] a degenerative periodontal disease of adolescents in which the periodontal destruction is out of proportion to the local irritating factors present on the adjacent teeth; inflammatory changes become superimposed, and bone loss, migration, and extrusion are observed. Two forms are recognized: localized, in which the destruction is limited to the incisors and first molars; and generalized, involving all the teeth. Synonym(s): periodontosis

aggressive periodontitis type 1

An autosomal dominant condition (OMIM:170650) characterised by severe and protracted gingival infections, leading to tooth loss.
Molecular pathology
Defects in CTSC, which encodes cathepsin C, a ubiquitous lysosomal cysteine proteinase, cause aggressive periodontititis type 1.

juvenile periodontitis

Dentistry Early onset periodontitis of adolescents, ♂:♀ ratio, 3:1, characterized by an early loss of alveolar bone surrounding permanent teeth; 84% have underlying endocrinopathies, 12% systemic disease–eg, DM, neutropenia, Down syndrome, Ehlers-Danlos syndrome, hyperkeratosis palmaris et plantaris, larger histiocytosis X, hypophosphatasia Etiology Actinobacillus actinomycecomitans and others

ju·ve·nile per·i·o·don·ti·tis

(jū'vĕ-nil per'ē-ō-don-tī'tis) A degenerative periodontal disease of adolescents in which the periodontal destruction is out of proportion to the local irritating factors present on the adjacent teeth; inflammatory changes become superimposed, and bone loss, migration, and extrusion are observed. Two forms are recognized: 1) localized, in which the destruction is limited to the incisors and first molars; and 2) generalized, involving all of the teeth.
Synonym(s): periodontosis.

ju·ve·nile per·i·o·don·ti·tis

(jū'vĕ-nil per'ē-ō-don-tī'tis) [MIM*170650] Degenerative periodontal disease of adolescents in which periodontal destruction is out of proportion to local irritating factors present on adjacent teeth; inflammatory changes become superimposed, and bone loss, migration, and extrusion are observed. Two forms are recognized: localized, in which the destruction is limited to the incisors and first molars; and generalized, involving all teeth.
Synonym(s): localized juvenile periodontitis, periodontosis.