| 释义 |
isoretinoin isoretinoin 13-cis-retinoic acid A proprietary vitamin A analogue used to treat refractory acne, leukoplakia, and induce long-term clinical and lab remissions in juvenile CML Teratogenicity It is a category X drug–ie, teratogenic, contraindicated in pregnancy–causes cardiac malformations–VSD, aortic arch and conotruncal defects, external ear deformity, cleft palate, micrognathia, CNS malformations. See Vitamin A analogues. |