microvesicular steatosis

microvesicular steatosis

The presence of multiple 1-µ droplets of fat in liver cells, damage/necrosis and giant mitochondria, which is not always identifiable on H&E staining.
 
Aetiology
Reye syndrome (panacinar) due to aspirin; alcohol (perivenular); drugs; infectious (e.g., HAV, HDV, Salmonella); HELLP; acute fatty liver of pregnancy.