malignant exocrine pancreatic tumour

malignant exocrine pancreatic tumour

A general term for any malignancy—generally understood to be of epithelial and/or neuroendocrine origin (i.e., non-lymphoid, non-mesenchymal, non-melanoma)—of the exocrine pancreas, which was classified by the World Health Organization in 2000.
Malignant exocrine pancreatic tumours, per WHO
• Ductal adenocarcinoma:
– Mucinous non-cystic carcinoma (colloid adenocarcinoma);
– Signet-ring cell carcinoma;
– Adenosquamous carcinoma;
– Undifferentiated (anaplastic or sarcomatoid) carcinoma;
– Undifferentiated carcinoma with osteoclast-like giant cells;
– Mixed ductal-endocrine carcinoma;
– Hepatoid carcinoma Not in 2000 WHO classification;
– Medullary carcinoma Not in 2000 WHO classification.
• Serous cystadenocarcinoma.
• Mucinous cystadenocarcinoma (non-invasive).
• Mucinous cystadenocarcinoma (invasive).
• Mucinous neoplasm (Not in 2000 WHO classification):
– Mucinous cystic neoplasm (carcinoma in situ);
– Mucinous cystic neoplasm with invasive carcinoma.
• Intraductal papillary mucinous neoplasm (non-invasive/carcinoma in situ).
• Intraductal papillary mucinous neoplasm with invasive carcinoma.
• Oncocytic variant of intraductal papillary neoplasm (Not in 2000 WHO classification).
• Intraductal tubular neoplasm (Not in 2000 WHO classification).
• Acinar cell carcinoma:
– Acinar cell cystadenocarcinoma;
– Mixed acinar-endocrine carcinoma.
• Pancreatoblastoma.
• Solid-pseudopapillary carcinoma.
• Carcinomas of ampulla of Vater, extrahepatic bile ducts.
• Adenocarcinoma.
• Papillary adenocarcinoma.
• Adenocarcinoma, intestinal type.
• Adenocarcinoma, gastric foveolar type.
• Mucinous adenocarcinoma.
• Clear cell adenocarcinoma.
• Signet-ring cell carcinoma.
• Adenosquamous carcinoma.
• Squamous cell carcinoma.
• Small cell carcinoma.
• Undifferentiated carcinoma.
• Mixed carcinoid-adenocarcinoma.