malignant transformation


malignant transformation

The constellation of changes in the growth properties of cells in culture evoked by various agents (e.g., radiation, toxins and viruses) that result in development of neoplasms with metastatic potential. The ability to metastasise is generally regarded as the defining marker of a tumour as being malignant.

malignant transformation

Oncology The constellation of changes in the growth properties of cells in culture evoked by various agents–eg, radiation, toxins, and viruses that result in development of tumors