| 单词 | kif4a |
| 释义 | KIF4AKIF4AA gene on chromosome Xq13.1 that encodes an ATP-dependent, microtubule-based motor protein involved in the intracellular transport of membranous organelles. KIF4A translocates the protein regulator of cytokinesis 1 (PRC1) to the plus ends of interdigitating spindle microtubules during the metaphase-to-anaphase transition, which is an essential step in forming an organised central spindle midzone and midbody and in successful cytokinesis. KIF4A may play a role in mitotic chromosomal positioning and bipolar spindle stabilisation. |
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