单词 | middle molecule toxin |
释义 | middle molecule toxinmiddle molecule toxinA group of small (0.5–60-kd) molecules (e.g., uric acid, guanidinos, polypeptides and metabolic end products, such as phenols) which are not removed during dialysis of patients with chronic renal failure; they are linked to the peripheral neuropathy and pericarditis commonly seen in uraemia. The so-called MMT fraction may inhibit haemoglobin synthesis, glucose metabolism, lymphoblast transformation, phagocytic activity and nerve conduction. |
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