| Acronym | Definition |
|---|
| OSB➣Oriented Strand Board |
| OSB➣Oracle Service Bus |
| OSB➣Oregon State Bar (Lake Oswego, Oregon) |
| OSB➣Office of State Budget (various locations) |
| OSB➣Old Saybrook (Amtrak station code; Old Saybrook, CT) |
| OSB➣Olayan School of Business (American University; Lebanon) |
| OSB➣Order of Saint Benedict |
| OSB➣Open Source Blog |
| OSB➣Open Speech Browser |
| OSB➣Operations Software Branch |
| OSB➣Oracle Secure Backup |
| OSB➣Off Site Branch |
| OSB➣Oem for System Builder |
| OSB➣Office of the Superintendent of Bankruptcy (Canada) |
| OSB➣Osama Bin Laden |
| OSB➣Otentikk Street Brothers (musicians) |
| OSB➣One Step Beyond |
| OSB➣Ordinis Sancti Benedicti (of the order of St Benedict) |
| OSB➣Orquestra Sinfônica Brasileira (Portugese) |
| OSB➣Overbrook School for the Blind (Philadelphia, PA) |
| OSB➣Orthodox Study Bible |
| OSB➣Online Services Business (Microsoft business segment) |
| OSB➣Office Shortcut Bar (Microsoft Office) |
| OSB➣Office of Surveillance and Biometrics (Center for Devices and Radiological Health; US FDA) |
| OSB➣Offset Spoke Bed (bicycle wheels) |
| OSB➣Operations Support Building |
| OSB➣Optimization and Systems Biology (Symposium) |
| OSB➣Officer Selection Battery |
| OSB➣Oregon Symphonic Band (Portland, OR) |
| OSB➣Operations Support Branch |
| OSB➣Optimal Spectrum Balancing |
| OSB➣Output Signal Balance |
| OSB➣One Shot Battery |
| OSB➣Other Sports Beckon |
| OSB➣OpenSG Binary (a 3D file format/extension) |
| OSB➣Overseas Service Bar |
| OSB➣Operational Stations Book |
| OSB➣Officer Selection Brief |
| OSB➣Old School Books |
| OSB➣Originally Signed By |
| OSB➣Operation Shoe Box |
| OSB➣Oberes Seitenband (German: upper sideband) |
| OSB➣Option Select Button |
| OSB➣Operation Stations Book |
| OSB➣Oriental Satellite Broadcasting |
| OSB➣Operational Service Bulletin |
| OSB➣Openshop Business |
| OSB➣Order of Shepherds of Bethlehem |
| OSB➣Official Sealed Bid (Wisconsin state procurement) |
| OSB➣Over-Determined Sub-Band |
| OSB➣Ortssippenbuch, Familienbuch or Ortsfamilienbuch (German) |