| Acronym | Definition |
|---|
| OPU➣Okayama Prefectural University (Okayama, Japan) |
| OPU➣Optical Pickup Unit |
| OPU➣Older Persons Unit (UK) |
| OPU➣Ovum Pick-Up |
| OPU➣Overcloud Processing Unit (computing) |
| OPU➣Office des Publications Universitaires |
| OPU➣Order Prohibiting Use (US OSHA; California) |
| OPU➣Optical Pickup Head (DVD drives) |
| OPU➣Optical Channel Payload Unit |
| OPU➣OnPlayerUpdate (computing) |
| OPU➣Offshore Production Unit (various locations) |
| OPU➣Oil Pick Up (spinning) |
| OPU➣Outstation Processing Unit |
| OPU➣Overseas Plexiglass Unit (US Navy) |
| OPU➣Organisations Psykologisk Uddannelse (Danish) |
| OPU➣Ottawa Panhandlers' Union (Canada) |
| OPU➣Operational Performance Unit |
| OPU➣Operating Partnership Unit (investing) |