medial arteriosclerosis

Mön·cke·berg ar·te·ri·o·scle·ro·sis

(mērn'kĕ-bĕrg), arterial sclerosis involving the peripheral arteries, especially of the legs of older people, with deposition of calcium in the medial coat (pipestem arteries) but with little or no encroachment on the lumen. Synonym(s): medial arteriosclerosis, Mönckeberg calcification, Mönckeberg degeneration, Mönckeberg medial calcification, Mönckeberg sclerosis

medial calcific sclerosis

A type of dystrophic calcification in which calcium is deposited in the tunica media of arteries.
Clinical findings
Medial cystic sclerosis is usually asymptomatic, but may be associated with atherosclerosis, hypertension, diabetes and chronic kidney disease. Areas affected are “pulseless” due to the calcified encasement; areas beyond the sclerosis have a “bounding” pulse.
Imaging
Affected medium-sized arteries in the upper and lower limbs have linear calcifications, resulting in a so-called pipestem appearance.

Pathogenesis
Uncertain; an array of calcium-regulating proteins have been implicated, including osteopontin, osteoprotegerin, matrix GLA protein, fetuin-A, receptor activator of NF-kappa-B, receptor activator of NF-kappa-B ligand and TNF-related apoptosis-inducing ligand.

Mönckeberg,

(Moenckeberg), Johann G., German pathologist, 1877-1925. Mönckeberg arteriosclerosis - involves the peripheral arteries with deposition of calcium in the medial coat but with little or no encroachment on the lumen. Synonym(s): medial arteriosclerosis; Mönckeberg calcification; Mönckeberg degeneration; Mönckeberg medial calcification; Mönckeberg sclerosis; Mönckeberg syndromeMönckeberg calcification - Synonym(s): Mönckeberg arteriosclerosisMönckeberg degeneration - Synonym(s): Mönckeberg arteriosclerosisMönckeberg medial calcification - Synonym(s): Mönckeberg arteriosclerosisMönckeberg sclerosis - Synonym(s): Mönckeberg arteriosclerosisMönckeberg syndrome - Synonym(s): Mönckeberg arteriosclerosis

单词	medial arteriosclerosis
释义	medial arteriosclerosis medial arteriosclerosis [′mē·dē·əl ‚är·tir·ē·ō·sklə′rō·səs] (medicine) Calcification of the tunica media of small and medium-sized muscular arteries. Also known as medial calcinosis; Mönckeberg's arteriosclerosis. medial arteriosclerosis Mön·cke·berg ar·te·ri·o·scle·ro·sis (mērn'kĕ-bĕrg), arterial sclerosis involving the peripheral arteries, especially of the legs of older people, with deposition of calcium in the medial coat (pipestem arteries) but with little or no encroachment on the lumen. Synonym(s): medial arteriosclerosis, Mönckeberg calcification, Mönckeberg degeneration, Mönckeberg medial calcification, Mönckeberg sclerosis medial calcific sclerosis A type of dystrophic calcification in which calcium is deposited in the tunica media of arteries. Clinical findings Medial cystic sclerosis is usually asymptomatic, but may be associated with atherosclerosis, hypertension, diabetes and chronic kidney disease. Areas affected are “pulseless” due to the calcified encasement; areas beyond the sclerosis have a “bounding” pulse. Imaging Affected medium-sized arteries in the upper and lower limbs have linear calcifications, resulting in a so-called pipestem appearance. Pathogenesis Uncertain; an array of calcium-regulating proteins have been implicated, including osteopontin, osteoprotegerin, matrix GLA protein, fetuin-A, receptor activator of NF-kappa-B, receptor activator of NF-kappa-B ligand and TNF-related apoptosis-inducing ligand. Mönckeberg, (Moenckeberg), Johann G., German pathologist, 1877-1925. Mönckeberg arteriosclerosis - involves the peripheral arteries with deposition of calcium in the medial coat but with little or no encroachment on the lumen. Synonym(s): medial arteriosclerosis; Mönckeberg calcification; Mönckeberg degeneration; Mönckeberg medial calcification; Mönckeberg sclerosis; Mönckeberg syndromeMönckeberg calcification - Synonym(s): Mönckeberg arteriosclerosisMönckeberg degeneration - Synonym(s): Mönckeberg arteriosclerosisMönckeberg medial calcification - Synonym(s): Mönckeberg arteriosclerosisMönckeberg sclerosis - Synonym(s): Mönckeberg arteriosclerosisMönckeberg syndrome - Synonym(s): Mönckeberg arteriosclerosis
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