MUC12

MUC12

A gene on chromosome 7q22 that encodes an epithelial mucin belonging to a family of secreted and cell surface glycoproteins, involved in epithelial cell protection, adhesion modulation and signalling. MUC12 may be involved in epithelial cell growth regulation, and is stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium.