Naegleria fowleri infection

A rare but severe protozoal infection causing destructive changes in the brain and meninges (necrotizing amoebic meningoencephalitis). Most infected people have a history of swimming in warm fresh water, or at a spa 2 to14 days before the onset. The organism gains access to the brain by way of the cribriform plate at the upper part of the nose. The infection mimics bacterial meningitis and the true diagnosis is usually missed. There is high fever, neck stiffness, coma, convulsions and death within a few days of onset. Autopsy shows brain softening. The only effective drug is Amphotericin B given intravenously and into the cerebrospinal fluid.

单词	naegleria fowleri infection
释义	Naegleria fowleri infection Naegleria fowleri infection A rare but severe protozoal infection causing destructive changes in the brain and meninges (necrotizing amoebic meningoencephalitis). Most infected people have a history of swimming in warm fresh water, or at a spa 2 to14 days before the onset. The organism gains access to the brain by way of the cribriform plate at the upper part of the nose. The infection mimics bacterial meningitis and the true diagnosis is usually missed. There is high fever, neck stiffness, coma, convulsions and death within a few days of onset. Autopsy shows brain softening. The only effective drug is Amphotericin B given intravenously and into the cerebrospinal fluid.
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