mediator complex

coactivation proteins involved in RNA polymerase transcription of DNA segments.

mediator complex

A multimeric protein complex that is required for DNA-binding activation and regulated transcription of nearly all RNA polymerase II-dependent genes. The mediator complex (MC) serves as a bridge, conveying information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. It is recruited to promoters by direct interactions with regulatory proteins, and it serves as a scaffold for assembling a functional pre-initiation complex with RNA polymerase II and general transcription factors.

me·di·a·tor com·plex

(mē'dē-ā-tōr kom'pleks) Coactivation proteins involved in RNA polymerase transcription of DNA segments.

单词	mediator complex
释义	mediator complex mediator complex coactivation proteins involved in RNA polymerase transcription of DNA segments. mediator complex A multimeric protein complex that is required for DNA-binding activation and regulated transcription of nearly all RNA polymerase II-dependent genes. The mediator complex (MC) serves as a bridge, conveying information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. It is recruited to promoters by direct interactions with regulatory proteins, and it serves as a scaffold for assembling a functional pre-initiation complex with RNA polymerase II and general transcription factors. me·di·a·tor com·plex (mē'dē-ā-tōr kom'pleks) Coactivation proteins involved in RNA polymerase transcription of DNA segments.
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