| 释义 |
nuclear factor-kappaB nuclear factor-κBan evolutionarily conserved eukaryotic transcription factor system that contributes to the mounting of an effective immune response but also plays an important role in many other cellular processes. NF-κB and its regulators are linked to signal transduction pathways as well as transcriptional activation events that mediate critical stages of cell proliferation, development, and apoptosis.nu·cle·ar fac·tor-κB (nū'klē-ăr fak'tŏr) A transcription factor associated with cytokine production. |