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单词 mucoprotein
释义

mucoprotein


mu·co·pro·tein

M0462900 (myo͞o′kō-prō′tēn′, -prō′tē-ĭn)n. Any of a group of organic compounds, such as the mucins, that consist of a complex of proteins and glycosaminoglycans and are found in body tissues and fluids.

mucoprotein

(ˌmjuːkəʊˈprəʊtiːn) n (Biochemistry) any of a group of conjugated proteins containing small quantities of mucopolysaccharides; glycoprotein

mu•co•pro•tein

(ˌmyu kəˈproʊ tin, -ti ɪn)

n. a protein that yields carbohydrates as well as amino acids on hydrolysis. [1920–25]

Mucoprotein


mucoprotein

[¦myü·kō′prō‚tēn] (biochemistry) Any of a group of glycoproteins containing a sugar, usually chondroitinsulfuric or mucoitinsulfuric acid, combined with amino acids or polypeptides.

Mucoprotein

 

a complex biopolymer consisting of protein and carbohydrate components bonded covalently. Mucoproteins are widely distributed in nature. They are components of such secretions in animals and man as saliva, gastric juice, and cerebrospinal fluid, as well as of blood plasma, erythrocytes, urine, chicken egg albumin, the eggs of amphibians and invertebrates, and the cell wall of microorganisms. A number of enzymes and hormones are classified as mucoproteins.

Mucoproteins differ in protein content and in the structure and size of the carbohydrate fraction. They usually contain up to 85 percent protein. Blood elements, however, are the exception, containing up to 80 percent carbohydrates. The carbohydrate fraction of mucoproteins includes the following monosaccharides: N-acetyl-D-glucosamine, N-acetyl-D-galactosamine, D-mannose, fucose, N-acetyl(glycolyl)neuraminic acid, and D-galactose. The peptide chains contain the common amino acids. The biosynthesis of the peptide chains takes place in the ribosomes, while the synthesis of the carbohydrate chains occurs in the Golgi complex with the help of specific enzymes —glycosyltransferases.

The biological functions of mucoproteins are highly varied. They determine the immune properties of the body, the blood-group affiliation, and the elasticity and permeability of tissues. They also participate in intercellular interactions. These functions are primarily determined by the structure of the carbohydrate chains of the mucoproteins. The term “glycoprotein” is more frequently used than “mucoprotein.”

REFERENCES

Derevitskaia, V. A. “Khimiia glikoproteinov.” Uspekhi biologicheskoi khimii, 1967, vol. 8.
Khimiia uglevodov. Moscow, 1967.
Glikoproteiny, vols. 1–2. Moscow, 1969. (Translated from English.)

N. D. GABRIELIAN

mucoprotein


mucoprotein

 [mu″ko-pro´tēn] a compound present in all connective and supporting tissues, containing, as prosthetic groups (non–amino acid components), mucopolysaccharides; soluble in water and relatively resistant to denaturation.Tamm-Horsfall mucoprotein a substance produced by cells of the ascending limb of the loop of Henle; it is a normal constituent of urine and is the major protein constituent of urinary casts.

mu·co·pro·tein

(myū-kō-prō'tēn), General term for a protein-polysaccharide complex, usually implying that the protein component is the major part of the complex, in contradistinction to mucopolysaccharide; mucoproteins include the α1- and α2-globulins of serum (and others). Sometimes called glycoproteins, although this term usually refers to those mucoproteins containing less than 4% carbohydrate.

mucoprotein

(myo͞o′kō-prō′tēn′, -prō′tē-ĭn)n. Any of a group of organic compounds, such as the mucins, that consist of a complex of proteins and glycosaminoglycans and are found in body tissues and fluids.

mu·co·pro·tein

(myū'kō-prō'tēn) General term for a protein-polysaccharide complex, usually implying that the protein component is the major part of the complex. Mucoproteins include the α1- and α2-globulins of serum.

mucoprotein

a complex of protein and polysaccharide.
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