neonatal thrombocytopenia

neonatal thrombocytopenia

A state that is the most common cause of purpura during the neonatal period, defined by platelets < 150,000/µL Neonatal thrombocytopenia–causes Platelet consumption • Immune-mediated Autoimmune, alloimmune–ITP or SLE in mother, platelet antibodies from mother • Nonimmune Thrombin generation, infections platelet production Amegakaryocytic thrombocytopenia, aplastic anemia, myeloinfiltrative processes Others Drugs, hypoxia, inherited metabolic disorders, hypersplenism, associated with giant hemangiomas–Kasabach-Merritt syndrome