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neostigmineenUK
ne·o·stig·mine N0059950 (nē′ō-stĭg′mēn, -mĭn)n. A cholinesterase inhibitor that is given in the form of a bromide salt, C12H19BrN2O2, or a methyl sulfate, C13H22N2O6S, used to treat myasthenia gravis and muscle atony and to reverse the effects of muscle relaxants after surgery. [neo- + (physo)stigmine.]neostigmine (ˌniːəʊˈstɪɡmiːn) n (Pharmacology) pharmacol a cholinergic drug which acts as a muscle stimulant and is used primarily to treat myasthenia gravisne•o•stig•mine (ˌni oʊˈstɪg min, -mɪn) n. a synthetic anticholinesterase, C12H19N2O2, used in the treatment of myasthenia gravis, glaucoma, and postoperative urinary bladder distention. [1940–45; neo- + (physo)stigmine] ThesaurusNoun | 1. | neostigmine - a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravisProstigminanticholinesterase - a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect | TranslationsneostigmineenUK
neostigmine (nē'ōstĭg`mēn, –mĭn), drug used to mimic the effects of stimulation of the parasympathetic nervous systemnervous system, network of specialized tissue that controls actions and reactions of the body and its adjustment to the environment. Virtually all members of the animal kingdom have at least a rudimentary nervous system. ..... Click the link for more information. . Along with several other drugs that have a similar mode of action, it inhibits the action of the enzyme cholinesterase, which destroys the substance acetylcholineacetylcholine , a small organic molecule liberated at nerve endings as a neurotransmitter. It is particularly important in the stimulation of muscle tissue. The transmission of an impulse to the end of the nerve causes it to release neurotransmitter molecules onto the surface of ..... Click the link for more information. at nerve endings. Because neostigmine increases the effective concentration of acetylcholine, it causes such body changes as contraction of the pupils, increased activity of intestinal muscles, and increased secretion by the salivary and sweat glands. It will cause menstrual bleeding in a nonpregnant woman whose menstrual period is delayed, and it is therefore used as a pregnancy test. Neostigmine and related drugs are also used to diagnose and control the neuromuscular disease myasthenia gravis. Because neostigmine causes decreased fluid pressure in the eye it is used to treat certain types of glaucoma. The drug atropineatropine , alkaloid drug derived from belladonna and other plants of the family Solanaceae (nightshade family). Available either as the tincture or extract of belladonna, or as the pure substance atropine sulfate, it is a depressant of the parasympathetic nervous system. ..... Click the link for more information. is sometimes given along with neostigmine to prevent the latter's side effects. Ephedrineephedrine , drug derived from plants of the genus Ephedra (see Pinophyta), most commonly used to prevent mild or moderate attacks of bronchial asthma. Unlike epinephrine, to which it is chemically similar, ephedrine is slow to take effect and of mild potency and long ..... Click the link for more information. often enhances the action of neostigmine.neostigmine[¦nē·ō¦stig‚mēn] (pharmacology) A quaternary ammonium cation that is used as the bromide (C12H19BrN20O2) and methylsulfate (C13H22N2O6S) salts; has anticholinesterase activity. neostigmineenUK
neostigmine [ne″o-stig´mēn] an anticholinesterase and prokinetic agent used for the symptomatic treatment of myasthenia gravis, for prevention and treatment of postoperative stasis and atony of the gastrointestinal tract or urinary bladder, and for reversal of the effects of certain neuromuscular blocking agents, such as tubocurarine, after surgery. Available as neostigmine bromide and neostigmine methylsulfate.neostigmine (nē′ō-stĭg′mēn, -mĭn)n. A cholinesterase inhibitor that is given in the form of a bromide salt, C12H19BrN2O2, or a methyl sulfate, C13H22N2O6S, used to treat myasthenia gravis and muscle atony and to reverse the effects of muscle relaxants after surgery.neostigmine Pharmacology An anticholinesterase used for the symptomatic therapy of myasthenia gravis and, in anesthesiology, to reverse the effects of depolarizing agents. See Myasthenia gravis, Reversal agent. neostigmine An ANTICHOLINESTERASE drug used in the treatment of MYASTHENIA GRAVIS. Neostigmine interferes with the enzyme that breaks down the neurotransmitter ACETYLCHOLINE and so prolongs its action. The drug is on the WHO official list. A brand name is Robinul neostigmine.neostigmineA reversible anticholinesterase drug, which neutralizes the effect of acetylcholinesterase and thereby allows the prolonged action of acetylcholine on the iris and ciliary muscle. Its action is similar to physostigmine but it is not so irritating a miotic. Both are occasionally used in the treatment of glaucoma. See acetylcholine; parasympathomimetic; physostigmine; miosis; miotics.neostigmineenUK Related to neostigmine: Pyridostigmine, Edrophonium, glycopyrrolateSynonyms for neostigminenoun a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravisSynonymsRelated Words |