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单词 loss of heterozygosity
释义

loss of heterozygosity


loss of heterozygosity

[¦lȯs əv ‚hed·e·rō·zī′gäs·əd·ē] (genetics) In a heterozygote, the loss of one of the two alleles at one or more loci in a cell lineage or cancer cell population due to chromosome loss, deletion, or mitotic crossing-over. Abbreviated LOH.

loss of heterozygosity


loss of heterozygosity

adjective Referring to a mutation that results in the loss of allelic uniqueness, often defined as a ≥ 40% increase in signal intensity of allelic signal.
AcronymsSeeLOH
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